Alright, The Simpsons:
Homer: Bloo
Marge: You can figure this one out
Bart: Terrence (Someone said this before)
Lisa: Once Again, FIGURE THIS OUT ON YOUR OWN
Maggie: One of the Imaginary babies
Ned: Wilt (Personality-wise)
Ralph: Cheese
Crazy Cat Lady: (Per suggestion) Madame Foster
Cletus: Creaky Pete
All I got
On the topic of Invader Zim: Cheese as Gir
Rugrats:
Tommy: Mac (He could wear a.... Bald cap)
Chuckie: Eduardo (Personality wise)
OMG, The Frankie fan-boys will be angry at me
......